CAS: | 540737-29-9 |
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Transport Package: | Double Plastic Bag Inside,Aluminum Foil Bag Outsid |
Specification: | 1g/50g/100g/500g/1KG |
Origin: | China |
Tofacitinib citrate Cas 540737-29-9 Pharmaceutical Intermediate
Product Description:
Product name | Tofacitinib Citrate |
Cas No. | 540737-29-9 |
Molecular Formula | C 22 H 28 N 6 O 8 |
Appearance | White powder |
Tofacitinib is a JAK inhibitor that effectively inhibits the activity of JAK1 and JAK3 and blocks signal transduction of a variety of inflammatory cytokines.
Existing studies have shown that tofacitinib has a good therapeutic effect on a variety of inflammation-related diseases such as rheumatoid arthritis, ulcerative colitis and psoriasis.
Application:
1. For the treatment of essential hypertension, it can be used alone or in combination with other antihypertensive drugs (such as diuretics).
2. For the treatment of heart failure, it can be used alone or in combination with cardiotonic or diuretic Chemicalbook drugs.
3. Preventing stroke in patients with hypertension and left ventricular hypertrophy.
4. It is used to slow the progression of nephropathy in patients with type 2 diabetes associated with nephropathy and hypertension.
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