CAS No 738-70-5 Trimethoprim

Model NO.
Trimethoprim
Appearance
White Powder
Shellf Life
24 Month
Test Method
HPLC UV
Molecular Formula
C14h18n4o3
Molecular Weight
290.32
CAS
738-70-5
Transport Package
1kg/Bag, 25kg/Drum
Specification
99%
Trademark
HNB
Origin
China
Production Capacity
5000kg/Month
Reference Price
$ 18.00 - 49.50
Contact Us

Product Description

CAS No 738-70-5 Trimethoprim
Product Name Trimethoprim  
CAS 738-70-5
Appearance White to off-white powder
Molecular formula C14H18N4O3
Assay 99%
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location
 

Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections.Other uses include for middle ear infections and travelers' diarrhea. With sulfamethoxazole it may be used for Pneumocystis pneumonia in people with HIV/AIDS. It is taken by mouth.

Function

1.It is primarily used in the treatment of urinary tract infections, although it may be used against any susceptible aerobic bacterial species. 
2.It may also be used to treat and prevent Pneumocystis jirovecii pneumonia. 
3.It is generally not recommended for the treatment of anaerobic infections such as Clostridium difficile colitis (the leading cause of antibiotic-induced diarrhea). 
4.Trimethoprim has been used in trials to treat retinitis.
5.Resistance to trimethoprim is increasing, but it is still a first line antibiotic in many countries.

Application

Cure pneogaster infection, chronic senile bronchitis, bacillary dysentery, urinary tract infection, pyelon-dphristis, enteritis typhoid, gonorrhea and some specific lesion etc.

CAS No 738-70-5 Trimethoprim

CAS No 738-70-5 Trimethoprim

Items

Standard

Results

Appearance

White or yellowish-white powder

White powder

Solubility

Very slightly soluble in water, 

slightly soluble in alcohol.

Very slightly soluble in water, 

slightly soluble in alcohol.

•Identification

A: Melting point

199-203

201.0-201.4

B: Specific absorbance

Max.287nm: 240-250

243

C: IR-spectrum

Complies with reference spectrum

Complies with reference spectrum

D: Chemical reaction

Green fluorescence at 365nm

Green fluorescence at 365nm

Appearance of solution

Not more intensely colored than 

Reference Solution BY7

Less intensely colored than reference solution BY7

Related substances

Method A by HPLC:

 

 

Impurity F

≤0.1%

0.05%

Any single impurity

≤0.1%

<0.1%

Total impurities

≤0.2%

<0.2%

Method B by HPLC:

 

 

Any single impurity

≤0.1%

<0.1%

Total impurities

≤0.2%

<0.2%

Heavy metals

≤20ppm

<

20ppm

Residual methanol

≤3000ppm

Not detected

Residual DMSO

≤5000ppm

Not detected

Residual acetic acid

≤5000ppm

Not detected

Impurity K(aniline) by GC

≤5ppm

Not detected

Loss on drying

≤0.5%

0.3%

Sulphated ash

≤0.1%

0.02%

Assay 

98.5-101.0%

99.71%

Particle size

100% pass 300 mesh

100% pass 300 mesh


CAS No 738-70-5 Trimethoprim CAS No 738-70-5 Trimethoprim CAS No 738-70-5 Trimethoprim CAS No 738-70-5 Trimethoprim CAS No 738-70-5 Trimethoprim CAS No 738-70-5 Trimethoprim

 

Veterinary Medicine

CHANHXETAI.VN, 2023