High quality raw powder anesthesia Mebendazole cas 33125
Basic Information
Synonyms: (r)-(+)-1-(alpha-methylbenzyl)imida zole-5-carboxylicacidethylester;1-(1-phenylethyl)-,ethylester,(r)-1h-imida zole-5-carboxylicaci;1-(1-Phenylethyl)-1H-imida zole-5-carboxylic acid ethyl ester;1-(1-phenylethyl)-1h-imida zole-5-carboxylicacidethylester;Amidate, R16659;Imida zole-5-carboxylic acid, 1-(alpha-methylbenzyl)-, ethyl ester, (R)-(+);1-[(R)-α-Methylbenzyl]-1H-imida zole-5-carboxylic acid ethyl ester(200 mg)
CAS: 33125
MF: C14H16N2O2
MW: 244.29
EINECS: 251-385-9
Melting point: 72-74°C
Boiling point: 160-162 °C
Storage temp.: 2-8°C
Description
The product
is a carboxylated imida zole intended for the inductionof general anesthesia. It is marketed as the morepotent R (+) isomer. It is believed to exert its anestheticeffect via positive modulation of the GABAA receptor. Itis not water soluble and is available in the United States as a2-mg/mL solution containing 35% v/v pro pylene glycol andin Europe as a soybean oil and medium-chain triglyceridesformulation. The pro pylene glycol has been associatedwith moderate-to-severe pain on injection and irritation ofthe vascular tissue. A high incidence of skeletal musclemovements were noted in about 32% of patients followingetomidate injection. Case reports of seizures are also foundin the literature.
Usage
Short-time intravenous anesthetics.
Function
Formulations containing are used for general anesthesia and sedation.1 also inhibits adrenal cortisol biosynthesis and mitigates hypercortisolism, as is found in Cushing syndrome.2,3 This product is intended for research and forensic applications.