CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil , etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

Model NO.
59-46-1
Logp
2.36
Psa
55.56000
Exact Mass
236.152481
Vapour Pressure
0.0±0.8 Mmhg at 25°c
Water Solubility
9.45g/L(30 ºC)
Einecs
200-426-9
CAS
59-46-1
CAS No.
59-46-1
Boiling Point
373.6±22.0 °c at 760 Mmhg
Density
1.1±0.1 g/cm3
Molecular Weight
236.310
Quality
Refined
Formula
C13h20n2o2
Colour
White
Appearance
Powder
Type
Pharmaceutical Intermediates
Transport Package
Packing Within 3 Working Days
Specification
25kg/Cardboard barrel
Trademark
Wuhan Mulei
Origin
Hebei
HS Code
2922499990
Production Capacity
500000kg
Reference Price
$ 14.58 - 16.20
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Product Description

Product Description

Procaine

 
 
Procaine structure
CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine
Common Name Procaine
CAS Number 59-46-1 Molecular Weight 236.310
Density 1.1±0.1 g/cm3 Boiling Point 373.6±22.0 °C at 760 mmHg
Molecular Formula C 13 H 20 N 2 O 2 Melting Point 61ºC
MSDS N/A Flash Point 179.8±22.3 °C

Use of Procaine


Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale .

 

 / procaine base cas 59-46-1 introduction

Procaine is a local anesthetic with a para-amino function. Sensitization mainly concerns medical, dental and veterinary professions.

The character of procaine  base as follows :
 its hydrochloride is colorless, odorle
564+9+ ss, small needle like or lobular crystal, slightly bitter taste, taste dull numbness. Soluble in water, slightly soluble in ethanol, Its aqueous solution is unstable, especially in the presence of light, acid and alkali substances are easy to deteriorate.
 

Basic information:

1.Product name: Procaine Base
2.CAS No. : 59-46-1
3. Apperance: white crystalline powder
4. Assay: ≥99%
5.MF: C13H20N2O2
6.MW: 236.31 
7.Usage: A sodium channel blocker and DNA methylation inhibitor Procaine hydrochloride is a local anesthetic agent.
8.Shelf life: 2 years

 

Product Description:

 
Product Name: Procaine Base
CAS: 59-46-1
Synonyms: 2-(Diethylamino)ethyl 4-aminobenzoate;2-(Diethylamino)ethyl p-aminobenzoate;2-(diethylamino)ethylp-aminobenzoate;2-diethylaminoethyl4-aminobenzoate;2-Diethylaminoethylester kyseliny p-aminobenzoove;2-diethylaminoethylesterkyselinyp-aminobenzoove;2-diethylaminoethylp-aminobenzoate;4-Aminobenzoic acid diethylaminoethyl ester
EINECS: 200-426-9
Product Categories: API
Mol File: 59-46-1.mol
 
Uses     Procaine (Novocain) is mainly used in dental or medical procedures requiring infiltration anesthesia, peripheral block, or spinal block.
Uses     inhibitor of sodium channel
Uses     Procaine is a sodium channel blocker and inhibitor of a variety of processes.

General Description     Procaine was synthesized in 1904 to address the chemical instabilityof cocai and the local irritation it produced. The pKa of procaine is 8.9; it has low lipid solubility and the estergroup is unstable in basic solutions. Procaine is available inconcentrations ranging from 0.25% to 10% with pHs adjustedto 5.5 to 6.0 for chemical stability. Procaine is also includedin some formulations of penicillin G to decrease the pain ofintramuscular injection.

Clinical Use     Procaine is very quickly metabolizedin the plasma by cholinesterases and in the liver via ester hydrolysisby a pseudocholinesterase. The in vitroelimination half-life is approximately 60 seconds. Any conditionthat decreases the cholinesterase concentration may increaseexposure to procaine and potential toxicity. Decreasedenzyme activity can be found with genetic deficiency, liverdisease, malignancy, malnutrition, renal failure, burns, thirdtrimester of pregnancy, and following cardiopulmonary bypasssurgery. Ester hydrolysis produces PABA, the compoundresponsible for the allergic reactions common to theester anesthetics. Procaine is not used topically because of itsinability to pass through lipid membranes and finds use as aninfiltration agent for cutaneous or mucous membranes, forshort procedures. Procaine is also used for peripheral nerveblock and as an epidural agent to diagnose pain syndromes.
 

Detailed Photos

CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

Product Parameters

 

 

100% through customs Tetracaine/Benzocaine/Lidocaine/ Procaine Hcl CAS 51-05-8 supplier in China, stock now!
 

We can offer different standard Procaine HCL for you such as
USP/BP/ISO 9001/GMP.
Also  We guarantee that our products will be delivered to you in time.
Last but no least, we   aimto   exceed   expectations  through  consistently   providing   quality  and  value  in our  products   and   services

 
 100% Safe Customs Clearance!!!

Support sample ! MOQ 1kg fast delivery
1-24kg ` Aluminium foil bags
Over 25kg ` 25kg bags or 25 kg drums
 
Product Information

Chemical & Physical Properties
 

 

Density 1.1±0.1 g/cm3
Boiling Point 373.6±22.0 °C at 760 mmHg
Melting Point 61ºC
Molecular Formula C 13 H 20 N 2 O 2
Molecular Weight 236.310
Flash Point 179.8±22.3 °C
Exact Mass 236.152481
PSA 55.56000
LogP 2.36
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.543
 
 
Storage: 

1. Stored in a clean, cool and dry area; keep away from strong, direct light.

2. Shelf Life is 2 years when properly stored.

 

Packing: 
1. Inner double plastic bags----25kg/Fiber drum (36*36*45cm, GW: 28kg, NW: 25kg);

2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).

3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).


P.S.: we accept packaging customization.

 

Delivery:   

1. In stock products are normally shipping within 3 working days.

2. For rush delivery, please contact our sales team for particular arrangement

 

Shipping:

1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.

2. Shipping details & shipping documents will be provided and sent by email.

3. We keep tracking the shippment until clients well received.

4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

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Procaine  59-46-1 IN STOCK Negotiable Available

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We accept various payment terms, the main methods are : T/T, L/C, Western Union, credit card, Bitcoin, USDT etc.
CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

Shipping term:
CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

Our Advantages

WHY CHOOSE US
MU LEI (Wuhan) is committed to helping clients reach their goals, to providing high quality products and efficient shipments.

Our strong sense of responsibility with client projects means that we are constantly striving to provide solutions, even for issues they aren't yet aware of.

This sense of responsibility also means we value and promote seamless interaction with clients, and ensure the best value is obtained from their research budget.

Our staff bring professional knowledge to clients, as well as efficient responding to the clients, have built long-term cooperated relationships.
CAS: 59-46-1 Procaine Base Powder Em Po Polvo Security Customs to USA, Europe, Brasil, etc, 99% Pure Tetracaine Amethocaine Lidocaine Benzocaine

FAQ

In this page, we will continue to update frequently asked questions and answers about the crystaline, Benzocaine powder, Lidocaine hcl powder, Procaine hcl crystal, fluffy Lidocaine, tetracaine chemical, crystaline tetramisole hydrochloride, cas  and so on, Stay tuned....

  • Q What's your advantage?

    A

    The series of natural extracted product are all self-developed, produced and tested. Mature production technology, strict quality management system and cost control system, ensure the product stability and competitive price.

  • Q How to deal with quality complaints or the goods get loss?

    A

    Firstly, every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA (or depends on customers' request). 


    If it is our product quality issue or due to the force majeures, we will send you another shipment for free.
     

  • Q Is there any discount?

    A The price is negotiable. The more bigger quantity you order, the more competitive price you would get.
     

  • Q How do you manage the delivery?

    A Goods will be shipped within 24 hours (Chinese public holiday are excluded), usually shipping by DHL, Fedex, EMS, TNT, HKETK. We will ship with the special safe channel to  ensure you getting goods on time. 

  • Q How to place an order?

    A Inquiry + payment + shipping.

    Firstly, please send inquiry infor to us, including quantity, your target price, shipping method, packing request, destination etc.      We will reply you the quotation and lead time within 1-8 hours (different time zone).

    Second, pay for the order, we accept various payment terms, the main methods are: T/T, L/C, Western Union, credit card, BitCoin, USDT, Money Gram.

    After received the payment, we will ship out products immediately and share tracking number with you.

    And for sure, we keep tracking the shippment, and we provide after-service. 
     

  • Q Can I get some samples?

    A Warmly welcome, we can provide samples for free, but the shipping cost will be covered by customers.

 

 

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